The Cell Cycle: Principles of Control(Primers in Biology S.)

Cell division is a central biological process: it yields the cells required for development and growth, and supplies the replacement cells to repair and maintain old or damaged tissue. But how does this cell division occur? How is it regulated? And what are the consequences when regulation fails? The Cell Cycle: Principles of Control provides an engaging insight into the process of cell division, bringing to the student a much-needed synthesis of a subject entering a period of unprecedented growth as an understanding of the molecular mechanisms underlying cell division are revealed. The book gives the student a complete overview of the process of cell division - from chromosome division, through mitosis, cytokinesis, and meiosis - before exploring how cell proliferation is controlled, and how the cell cycle responds to DNA damage. Finally, the book examines the intrinsic relationship between the cell cycle and cancer, and how a detailed understanding of the cell cycle may lead to new specific therapies to treat the disease.The Cell Cycle combines articulate prose with striking full colour illustrations, while the unique Primers in Biology modular structure integrates text, illustrations, definitions, and literature references for each topic into one double-page spread, bringing to the student's fingertips all the tools that they need to master that topic. An understanding of the cell cycle is a central tool in gaining insights into many biological systems and processes. The Cell Cycle: Principles of Control is the ideal resource for any student wishing to develop a sound grasp of this vitally important subject. Online Resource Centre The Online Resource Centre features: For lecturers Figures from the book available to download, to facilitate lecture preparation Lecturers in the US and Canada: The Cell Cycle is distributed in the US and Canada by Sinauer Associates. Ordering details can be found at: www.sinauer.com/detail.php?id=5086

Table of Contents:
1. The Cell Cycle; 2. Model Organisms in Cell-Cycle Analysis; 3. The Cell-Cycle Control System; 4. Chromosome Duplication; 5. Early Mitosis: Preparing for Chromosome Segregation; 6. Assembly of the Mitotic Spindle; 7. The Completion of Mitosis; 8. Cytokinesis; 9. Meiosis; 10. Control of Cell Proliferation and Growth; 11. Cell-Cycle Respomses to DNA Damage; 12. The Cell Cycle in Cancer

Review :
I have enjoyed reading this textbook cover to cover. I have learned new things from chapters that lie outside of my own specialisation of chromosome duplication, and have made interesting new connections. As a University teacher and researcher, I can strongly recommend David Morgan's textbook to students with a background in molecular biology who are interested in the regulation of the eukaryotic cell cycle. Torsten Krude in BioEssays, June 2007 This is an extremely useful book, which can be used in undergraduate (for an advanced course) and graduate teaching, and as a reference book for researchers in the field. The book will remain an essential source of information for curious students and scientists for some time. Nature Cell Biology, June 2007 an excellent reference book for cell biology undergraduates with an interest in the cell cycle and the related field of cancer research. It would also make a useful reference book for any post-graduate student in a cell-cycle laboratory. THES Textbooks Guide, February 2007