Glial Cell Development
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Glial Cell Development: Basic Principles and Clinical Relevance(Molecular and Cellular Neurobiology Series)

Glial Cell Development: Basic Principles and Clinical Relevance(Molecular and Cellular Neurobiology Series)


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About the Book

This is a new edition in the Cellular and Molecular Neurobiology series. The majority of cells in the nervous system are glial cells. During development, these cells provide growth factors that stimulate the proliferation, migration and survival of neurones and their precursors, and promote and guide axonal growth. In the mature nervous system, glial cells provide insulating myelin sheath around axons and provide metabolic and structural support for neurones. Glial cells also have a major influence on the local response to injury of central nerve tracts and the peripheral nervous system, either promoting, or inhibiting, axonal regrowth and recovery of lost function. This book provides a comprehensive, state-of-the-art overview of research into the development, function and malfunction of glial cells. It offers a compelling insight into how basic research throws light onto diseases and disorders and points the way towards treatments. Teams of internationally renowned experts, all active in research, have contributed chapters.

Table of Contents:
1: Mirsky & Jessen: Embryonic and early postnatal development of Schwann cells 2: Richardson: Oligodendrocyte development 3: Goldman: Developmental origins of astrocytes 4: Perry: Microglia in the developing and mature central nervous system 5: Magistretti, Pellerin & Therianos: The metabolic functions of glial cells 6: Gallo, Ghiani & Yuan: The role of ion channels and transmitter receptors in glial cell development 7: Ellisman, Deerinck & Bennett: Structure and formation of the node of Ranvier 8: Colman, Pedraza & Yoshida: Concepts in myelin sheath evolution 9: Nave: Myelin-specific genes and their mutations in the mouse 10: Hudson: Control of gene expression by oligodendrocytes 11: Topilko & Meijer: Transcription factors that control Schwann cell development and myelination 12: Granderath & Klämbt: Genetic analysis of gliogenesis in Drosophila 13: Fitch and Silver: Astrocytes are dynamic participants in central nervous system development and injury response 14: Filbin, Qiu & Cai: Glial influences on axonal regeneration 15: Scherer & Salzer: Axon-Schwann cell interactions during peripheral nerve degeneration & regeneration 16: Wrabetz, Feltri, Hanemann & Müller: The molecular genetics of hereditary demyelinating neuropathies 17: Ratner & Daston: Genetic & cellular mechanisms of Schwann cell tumour formation: neurofibromatosis type 1 and neurofibromatosis type 2 18: Lucchinetti & Lassmann: The neuropathology of Multiple Sclerosis 19: Blakemore, Franklin & Noble: Restoring CNS myelin by glial cell transplantation 20: Brüstle & Dubois-Dalcq: Stem cells and their gliogenic potential 21: Nistér, Uhrbom, Hesselager & Westermark: Glial tumours of the CNS


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Product Details
  • ISBN-13: 9780198524786
  • Publisher: Oxford University Press
  • Binding: Hardback
  • Height: 248 mm
  • No of Pages: 488
  • Spine Width: 30 mm
  • Weight: 1080 gr
  • ISBN-10: 0198524781
  • Publisher Date: 30 Aug 2001
  • Edition: Revised edition
  • Language: English
  • Series Title: Molecular and Cellular Neurobiology Series
  • Sub Title: Basic Principles and Clinical Relevance
  • Width: 174 mm


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Glial Cell Development: Basic Principles and Clinical Relevance(Molecular and Cellular Neurobiology Series)
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