The Sjögren's Book

Afflicting one in 83 Americans, Sjögren's is a serious and systemic autoimmune disease that, along with symptoms of extensive oral and ocular dryness, can lead to other serious complications including profound fatigue, chronic pain, major organ involvement, neuropathies and lymphoma. While there is no cure for Sjögren's, approaches exist to help manage and treat aspects of the disease, and this revised handbook offers everything readers need to understand and cope with their diagnosis. The Sjögren's Book, Fifth Edition is a comprehensive and authoritative guide, produced by the Sjögren's Foundation and its medical advisors and edited by a leading authority on autoimmune disorders. This expanded edition provides readers with the best medical and practical information on this disease, bringing together current thinking about Sjögren's in an easily readable and understandable book and providing important new content on areas not covered in previous editions. With more than fifty chapters written by leading experts, this handbook illuminates the major clinical aspects of the disease and is loaded with practical tips and advice as well as scientific advancements in the field. Indeed, it offers a wide-ranging look at the many faces of Sjögren's, covering diagnosis, the many organ systems that can be affected, emotional burden and management, treatment options, and hope for the future. Recognized as the bible for Sjögren's sufferers, this reliable and informative guide is the first place for patients to look when they have questions about this disabling disease. It is a valuable aid that patients can use while discussing their illness with their physician and an excellent resource for family members. Because Sjögren's is greatly underdiagnosed, this handbook is a particularly valuable resource for healthcare professionals.

Table of Contents:
CONTENTS Contributors Introduction: Why Write a Book on Sjögren's? by Daniel J. Wallace PART ONE What is Sjögren's and Who is the Sjögren's Patient? 1. The Sjögren's Foundation: The Patients' and Professionals' Key Resource and Advocate JANET E. CHURCH AND STEVEN TAYLOR 2. What is Sjögren's? FREDERICK B. VIVINO 3. Who Develops Sjögren's? CHRISTINE H. LEE AND DANIEL J. WALLACE 4. The Impact of Living with Sjögren's MATTHEW MAKARA 5. The Cost of Living with Sjögren's SIMON J. BOWMAN AND BENJAMIN FISHER PART TWO The Science of Sjögren's 6. Sjögren's and the Immune System ROBERT I. FOX AND STEVEN E. CARSONS 7. Environmental Effects JEFFREY W. WILSON, PETER OLSSON AND THOMAS MANDL 8. Genetics and Sjögren's KATHY L. SIVILS 9. The Gut Microbiome and Sjögren's ANAT GALOR, KARA M CAVUOTO AND SANTANU BANERJEE 10. Causes of Exocrine Gland Dysfunction in Sjögren's EFSTATHIA K. KAPSOGEORGOU, MICHAEL VOULGARELIS AND ATHANASIOS G. TZIOUFAS PART THREE How is the Body Affected? 11. Diagnosis of Fatigue DANIEL J. WALLACE, RICHA MISHRA AND FREDERICK B. VIVINO 12. Musculoskeletal Manifestations of Sjögren's DONALD E. THOMAS JR 13. Sjögren's and Central Nervous System Disorders ARUN VARADHACHARY 14. The Internal Organs in Sjögren's R. HAL SCOFIELD, FOTINI C. SOLIOTIS, STUART S. KASSAN AND HARALAMPOS M. MOUTSOPOULOS 15. The Dry Mouth AVA J. WU AND TROY E. DANIELS 16. The Dry Eye CINTIA S. DE PAIVA, ABHA GULATI, REZA DANA AND GARY N. FOULKS PART FOUR Diagnosis 17. Diagnostic and Classification Criteria for Sjögren's MATTHEW MAKARA 18. Laboratory Tests ALAN N. BAER 19. Assessing the Salivary Gland Component in Sjögren's: Biopsy & Imaging MALIN V. JONSSON, KATHRINE SKARSTEIN AND CHIARA BALDINI 20. The Difficult-to-Diagnose Sjögren's Patient ASTRID RASMUSSEN 21. Diseases Associated with Sjögren's JANET LEWIS AND FREDERICK B. VIVINO 22. Childhood Sjögren's SCOTT M. LIEBERMAN, SARA STERN AND JAY MEHTA PART FIVE Managing Sjögren's 23. Management of Dry Eye PETER DONSHIK 24. Management of Dry Mouth VIDYA SANKAR 25. Management of Other Sicca Symptoms: Dry Ears, Nose & Sinuses SOO KIM ABBOUD AND LEILA M. HADDAD 26. Vaginal Dryness in Sjögren's JOLIEN F. VAN NIMWEGAN AND RITA MELKONIAN 27. Management of Chronic Musculoskeletal Pain LAN CHEN 28. Management of Pulmonary Complications in Sjögren's AUGUSTINE LEE 29. Management of Peripheral Nervous System Complications in Sjögren's SHALINI MAHAJAN AND DANIEL J. WALLACE 30. Central Nervous System Complications in Sjögren's PANTELIS P. PAVLAKIS, THERESA LAWRENCE FORD, JANET LEWIS, SHALINI MAHAJAN, STEVEN MANDEL AND DANIEL J. WALLACE 31. Cognitive Dysfunction and Central Nervous System Involvement in Sjögren's EDWARD MAITZ AND STEPHEN MAITZ 32. Managing Fatigue NANCY CARTERON 33. Depression and Anxiety in Sjögren's VALERIE G. LOEHR AND E. SHERWOOD BROWN 34. Gastrointestinal Manifestations in Sjögren's KATERINA SHETLER 35. Gynecological and Urological Aspects of Sjögren's RITA MELKONIAN 36. Vasculitis in Sjögren's GHAITH NOAISEH 37. Lymphoma and Other Cancer in Sjögren's KIERON DUNLEAVY & KATHERINE M. HAMMITT 38. Hepatic and Pancreatic Involvement in Sjögren's CHADWICK R. JOHR 39. Kidney-Associated Involvement in Sjögren's DANIEL J. WALLACE 40. Complementary, Alternative & Integrative Approaches to Health MATTHEW MAKARA 41. Vitamin D and Sjögren's JEFFREY W. WILSON PART SIX Taking Charge of Your Sjögren's 42. Sjögren's: The Self and Others TERI P. RUMPF AND LYNN C. EPSTEIN 43. Enhancing Resilience Through Mind-Body Interactions MARGARET BAIM 44. Sleep Disorders H. KENNETH FISHER AND DANIEL J. WALLACE 45. Sex and Sjögren's ANNE E. BURKE 46. Vaccinations in Sjögren's RICHARD BRASINGTON 47. Disability THOMAS D. SUTTON AND KATHERINE M. HAMMITT PART SEVEN The Future 48. Recent and Promising Scientific Developments STEVEN E. CARSONS, MABI SINGH, NANCY MCNAMARA AND KATHERINE M. HAMMITT 49. The Sjögren's Foundation Clinical Trials Consortium THERESA LAWRENCE FORD 50. Clinical Trials: What they are, how to get Involved and the Current State in Sjögren's MATTHEW MAKRA AND DANIEL J. WALLACE 51. International Collaboration and the Information Technology that Fuels it: Keys to a Brighter Future KATHERINE M. HAMMITT

About the Author :
Daniel J. Wallace MD, FACP, MACR is a Professor of Medicine at Cedars-Sinai Medical Center and the David Geffen School of Medicine and co-directs the rheumatology fellowship program at Cedars-Sinai. Dr. Wallace has authored or co-authored nearly 450 peer-reviewed publications, and he has had 10 articles in the New England Journal of Medicine, JAMA, the Lancet and Journal of Clinical Investigation. He has authored 8 rheumatology textbooks, including The Lupus Book (OUP), and 25 book chapters.

Review :
Since 1989, The Sjögren's Book has been the prime resource for those affected by this disease. This Fifth Edition is even more comprehensive in its scope. Not only does this book detail how this systemic disease is diagnosed and managed by health care professionals, but it provides a comprehensive guide on how to cope with its myriad manifestations. I recommend this wonderful resource to all my patients. This book puts the patient front and center. Clinicians and patients will gain a better appreciation of Sjögren's disease's wide range of symptoms, and the need for collaborative multidisciplinary care to optimize patient outcomes. This is a must-have resource for anyone touched by Sjögren's. The Sjögren's Foundation and all contributors have ensured that comprehensive and accurate information is included in this easy-to-understand format to shed light into the many complexities of this serious disease. This revised edition will better enable all readers to become even stronger advocates for themselves and for Sjögren's. I'm proud to put forth our most comprehensive edition of The Sjögren's Book to date. As a patient, I personally use this book as my go-to resource to learn about my disease and to better cope with my multitude of symptoms. I bring the book with me to help educate my medical providers and emphasize that Sjögren's is serious and systemic. Our knowledge of Sjögren's has come a long way in the past 10 years and this 5th edition captures this information and gives the entire Sjögren's community hope for the future.