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Home > Mathematics and Science Textbooks > Chemistry > Analytical chemistry > Spectrum analysis, spectrochemistry, mass spectrometry > High Pressure Effects in Molecular Biophysics and Enzymology
High Pressure Effects in Molecular Biophysics and Enzymology

High Pressure Effects in Molecular Biophysics and Enzymology


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About the Book

High Pressure Effects in Molecular Biophysics and Enzymology is designed to acquaint biochemists, biophysicists, and graduate students with advances in the application of high pressure in connection with spectroscopy as a research tool in the study of biomolecules. The 23 chapters written by leading authorities present an overview of current approaches to the use of high pressure in research on enzyme kinetics, protein folding and structure, lipid bilayer structure and organization, lipid-protein interaction, and DNA structure. This important, timely volume is the first devoted exclusively to high-pressure effects in biochemistry and will be the definitive reference in its subject for the next several years.

Table of Contents:
Contributors 1: Gregorio Weber: Resolution of the Ambiguity of van't Hoff Plots by the Effect of Pressure on the Equilibrum 2: H. G. Drickamer: Pressure-Tuning Spectroscopy: A Tool for Investigating Molecular Interactions 3: Kenneth E. Prehoda and John L. Markley: Use of Partial Molar Volumes of Model Compounds in the Interpretation of High-Pressure Effects on Proteins 4: Karel Heremans, Koen Goossens, and László Smeller: Pressure-Tuning Spectroscopy of Proteins:Fourier Transform Infrared Studies in the Diamond Anvil Cell 5: Maurice R. Eftink and Glen D. Ramsay: Temerature- and Pressure-Induced Unfolding of a Mutant of Staphylococcal Nuclease A 6: Gediminas J. A. Vidugiris, Raj Thomas, and Catherine A. Royer: Pressure-Jump Relaxation Kinetics of Unfolding and Refolding Transitions of Staphylococcal Nuclease and Proline Isomerization Mutants 7: Yoshihiro Taniguchi and Naohiro Takeda: High-Pressure FTIR Studies of the Secondary Structure of Proteins 8: Xiangdong Peng et al.: High-Pressure NMR Studies of the Dissociation of Arc Repressor and the Cold Denaturation of Ribonulease A 9: Mauro Villas-Boas et al.: Exploring Structural, Functional, and Kinetic Aspects of Nucleic Acid-Protein Complexes with Pressure: Nucleosomes and RNA Polymerase 10: Jerson L. Silva, Andrea T. Da Poian, and Debora Foguel: Pressure and Cold Denaturation of Proteins, Protein-DNA Complexes, and Viruses 11: Robert B. Macgregor Jr., John Q. Wu, and Reza Najaf-Zadeh: Sequence, Salt, Charge and the Stability of DNA at High Pressure 12: Gaston Hui Bon Hoa et al.: Application of Pressure Relaxation to the Study of Substrate Binding to Cytochrome P-450[C[A[M versus Temperature, Pressure, and Viscosity 13: Isao Morishima: Pressure Effects on the Ligand-Binding Kinetics for Hemo proteins and Their Site-Directed Mutants 14: Claude Balny: Transient Enzyme Kinetics at High Pressure 15: Dexter Northrup: Steady-State Enzyme Kinetics at High Pressure 16: Jason L. Johnson and Gregory D. Reinhart: Effects of High Pressure on the Allosteric Properties of Phosphofructokinase from Escherichia coli 17: Patrick T. T. Wong: Correlation Field Splitting of Chain Vibrations: Structure and Dynamics in Lipid Bilayers and Biomembranes 18: Roland Winter et al.: High-Pressure Effects on the Structure of Phase Behavior of Model Membrane Systems 19: Parkson Lee-Gau Chong: Membrane-Free Volume Variation with Bulky Lipid Concentration by Regular Distribution: A Functionally Important Membrane Property Explored by Pressure Studies of Phosphatidylcholine Bilayers 20: Ana Jonas et al.: NMR Studies of the Order and Dynamics of Dipalmitoylphosphatidylcholine Bilayers as a Function of Pressure 21: Suzanne F. Scarlata: Effects of Increased Viscosity on the Function of Integral Membrane Proteins 22: Horst Ludwig, Wilhelm Scigalla, and Bernd Sojka: Pressure- and Temperature-Induced Inactivation of Microorganisms 23: Stephen G. Sligar, Clifford R. Robinson, and Mark A. McLean: Osmotic and Hydrostatic Pressure as Tools to Study Molecular Recognition Index

Review :
"This volume is a result of the Steenbock Symposium on High-Pressure Effects in Molecular Biophysics and Enzymology . . . [It] is not an introduction to applications of pressure perturbation in biology. Rather, its purpose is to present the state of the art in this field. . . . As such, it will serve as a valuable reference for investigators who are either working in this field or who wish to become familiar with the important issues in pressure effects on biological systems, and ways to use pressure as a tool in biophysics. The 23 articles discuss the effects of pressure on biological systems, the interpretation of thermodynamic parameters derived from pressure perturbation, and physical chemical techniques that have been successfully combined with high-pressure perturbation. . . . This volume represents an important contribution to the literature covering methods and applications of high-pressure perturbation in biophysics."--The Quarterly Review of Biology "This volume is a result of the Steenbock Symposium on High-Pressure Effects in Molecular Biophysics and Enzymology . . . [It] is not an introduction to applications of pressure perturbation in biology. Rather, its purpose is to present the state of the art in this field. . . . As such, it will serve as a valuable reference for investigators who are either working in this field or who wish to become familiar with the important issues in pressure effects on biological systems, and ways to use pressure as a tool in biophysics. The 23 articles discuss the effects of pressure on biological systems, the interpretation of thermodynamic parameters derived from pressure perturbation, and physical chemical techniques that have been successfully combined with high-pressure perturbation. . . . This volume represents an important contribution to the literature covering methods and applications of high-pressure perturbation in biophysics."--The Quarterly Review of Biology


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Product Details
  • ISBN-13: 9780195097221
  • Publisher: Oxford University Press Inc
  • Publisher Imprint: Oxford University Press Inc
  • Height: 242 mm
  • No of Pages: 400
  • Spine Width: 28 mm
  • Width: 163 mm
  • ISBN-10: 019509722X
  • Publisher Date: 10 Oct 1996
  • Binding: Hardback
  • Language: English
  • Returnable: N
  • Weight: 797 gr


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