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Dialysis Amyloid: (Oxford Clinical Nephrology Series)

Dialysis Amyloid: (Oxford Clinical Nephrology Series)


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About the Book

Dialysis amyloidosis is a syndrome observed in dialysis patients characterized initially by joint pain, followed later by joint destruction. It is at present one of the few compliations in these patients. The factors involved in the genesis of this syndrome are not yet known with certainty and there is as yet no proven efficacious treatment otehr then renal transplantation. As a result, the interest in this topic among nephrologists remains very high. Dialysis amyloid gives general information on the pathophysiology, and the clinical aspects of all types of amyloidosis. It then goes on to discuss recently discovered B2, type of dialysis amyloidosis, from clinical and pathological features to physiological and pathophysiological aspects of this serious complication which effects patients suffering from chronic renal failure. This book will give nephrologists and rheumatologists a clear understanding of the dialysis amyloidosis syndrome as well as making a valuable contribution to identifying strategies for treatment and prevention.

Table of Contents:
Part I: General aspects of amyloidosios 1: Pathpophysiology of amyloidogenesis 2: Various clinical types of amyloidosis Part II: Clinical characteristics of *B2=microglobulin amyloidosis 3: Arthropathy and carpal tunnel syndrome of *B2-microglobulin amyloidosis 4: Radiology of dialysis amyloidosis 5: Ultrasonography of the joints 6: Whole-body scintigraphy Part III: Pathology of *B2-microglobulin deposits 7: Composition of *B2-microglobulin deposits 8: Description, localization, and progression of B2-microglobulin dialysis-related amyloid deposition Part IV: Physiopathology of *B2-microglobulin accumulation and deposition 9: Characteristics of *B2-microglobulin metabolism 10: Involvement of *B2- microglobulin modified with AGEs in dialysis-related amyloidosis 11: Factors modifying removal and production of *B2-microglobulin 12: Determinants of fibril precipitation and aggregation in amyloid deposits. Part IV: Review of the clinical evidence on the prophylactic and therapeutic approaches to *B2-microglobulin amyloidosis 13: Prevention and treatment of *B2-microglobulin amyloidosis

Review :
`this book achieves a balance between clinical topics which will appeal to all practising nephrologists, and more fundamental aspects of amyloidosis which will interest anyone trying to unravel this challenging disorder.' P.E. Gower, Charing Cross Hospital, London, Journal of the Royal College of Physicians of London. Vol. 32, No. 1 January/February 1998 `In General this is an excellent book and gives much useful information relating to this distressing condition...A useful feature of this book is the extensive list of references at the end of each chapter...The chapters are well written, the book is well balanced, the illustrations appropriate and the index comprehensive. It is therefore a text which can be recommended to those seeking a greater understanding of the subject.' Nephrol Dial Transplant, 1998, 13: 1904-8


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Product Details
  • ISBN-13: 9780192624949
  • Publisher: Oxford University Press
  • Publisher Imprint: Oxford University Press
  • Height: 247 mm
  • No of Pages: 290
  • Spine Width: 22 mm
  • Width: 173 mm
  • ISBN-10: 0192624946
  • Publisher Date: 07 Mar 1996
  • Binding: Hardback
  • Language: English
  • Series Title: Oxford Clinical Nephrology Series
  • Weight: 720 gr


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