Gut Microbiota in Neurologic and Visceral Diseases

Gut Microbiota in Neurologic and Visceral Diseases presents readers with comprehensive information on the involvement of microbiota in the pathogenesis of neurological disorders. Chapters cover the effect of microbiota on the development of visceral (obesity, type 2 diabetes, heart disease) and neurological disorders (Alzheimer’s disease, Parkinson’s, depression, anxiety, and autism). Sections focus on the molecular mechanisms and signal transduction processes associated with the links among microbiota-related visceral and neurological disorders. It is hoped that this discussion will not only integrate and consolidate knowledge in this field but will also jumpstart more studies on the involvement of microbiota in the pathogenesis of neurological disorders.

Table of Contents:
1. Gut Microbiota: Implications on Human Health and Disease 2. Effect of Different Types of Diet Patterns on the Gut Microbiota Composition 3. Importance of Fiber in the Human Diet: Contribution of Microbiota in Human Health 4. Importance of Fermented Foods on Human Health 5. Contribution of Gut Microbiota in the Pathogenesis of Amyotrophic Lateral Sclerosis and Huntington’s Disease 6. The Gut Microbiome in Neurodegenerative Disorders 7. The Contribution of Gut Microbiota in the Pathogenesis of Parkinson’s Disease 8. The Contribution of Microbiota, Cereberal Blood Flow, and Sleep Deprivation in the Pathogenesis of Alzheimer’s Disease   9. Implications of Microbiota in the Pathogenesis of Diabetes Mellitus and Cardiovascular Disease 10. Link between Gut Microbiome and Cardiometabolic Diseases 11. Contribution of Microbiota in Obesity and Obesity-Related Chronic Diseases 12. Contribution of Microbiota in the Pathogenesis of Ischemic Stroke 13. Bioactive Lipids and Gut Microbiota Interact to Regulate Health and Disease 14. Contribution of Gut Microbiota and Multiple Organ Failure in the Pathogenesis of COVID-19 Infection 15. Contribution of Gut Microbiota in the Pathogenesis of Migraine Headache 16. Insights on the Modulatory Role of Ayurveda–Based Herbal Preparations on Gut Microbiome and Neuroprotection   17. The Emerging Roles of Gut Microbiome on Neurotoxic Outcomes: Implications for Neurological Disorders 18. Summary and Perspective for Future Research on the Contribution of Microbiota in Visceral and Neurological Disorders

About the Author :
Tahira Farooqui has published extensively on drug receptor interactions, biogenic amines in vertebrate and invertebrate nervous systems, biogenic amines mediated signaling, neural plasticity, as well as neuromoulatory roles of octopamine in the reinorcepathway involved in learning and memory, glycerophospholipid and sphingolipid metabolism and molecular signaling mechanisms in the brain. She is the author of 65 peer-reviewed research articles, one monographs and 8 edited books. She has coauthored a monograph in 2008 Metabolism and Function of Bioactive Ether Lipids in the Brain, 2008, by Springer, and have edited 8 Life Sciences books:1) Biogenic Amines: Pharmacological, Neurochemical, and Molecular Aspects in CNS, 2010, NOVA Science Publishers; 2) Phytochemicals and Human Health: Pharmacological and Molecular Aspects, 2011, NOVA Science Publishers; 3) Molecular Aspects of Neurodegeneration and Neuroprotection, 2011, Bentham Science Publishers; 4) Oxidative Stress in Vertebrates and Invertebrates: Molecular Aspects of Oxidative Stress on Cell Signaling, 2012, John Wiley & Sons, Inc; 5) Beneficial effects of propolis on human health and chronic diseases. Vol I, 2012, NOVA Science Publishers, Hauppage, New York; 6) Tahira Farooqui and Akhlaq A. Farooqui, Beneficial effects of propolis on human health and chronic diseases. Vol II, 2012, NOVA Science Publishers, Hauppage, New York; 7) Metabolic Syndrome and Neurological Disorders, 2013, John Wiley & Sons, Inc.; and 8) Diet and Exercise in Cognitive Function and Neurological Diseases, 2015, John Wiley & Sons, Inc. Akhlaq A. Farooqui is a leader in the field of signal transduction processes, lipid mediators, phospholipases, glutamate neurotoxicity, and neurological disorders. He is a research scientist in the Department of Molecular and Cellular Biochemistry at The Ohio State University. He has published cutting edge research on the role of phospholipases A2 in signal transduction processes, generation and identification of lipid mediators during neurodegeneration by lipidomics. He has studied the involvement of glycerophospholipid, sphingolipid-, and cholesterol-derived lipid mediators in kainic acid neurotoxicity, an experimental model of neurodegenerative diseases. Akhlaq A. Farooqui has discovered the stimulation of plasmalogen- selective phospholipase A2 in brains of patients with Alzheimer disease (AD). Stimulation of this enzyme may not only be responsible for the deficiency of plasmalogens in neural membranes of AD patients, but also be related to the loss of synapse in the AD.