Biological Oxidation Systems V2
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Biological Oxidation Systems V2

Biological Oxidation Systems V2


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About the Book

Biological Oxidation Systems, Volume II discusses the various antioxidants and antioxidant enzymes that play significant roles in protecting cells from deleterious reactions between their structural/functional components and the free radicals. This book examines the myriad chemical reactions of a cell’s metabolic activity that produce a variety of free radicals. Comprised of three parts encompassing 35 chapters, this volume starts with an overview of the metabolism of xenobiotics during arachidonic acid metabolism. This book then discusses the various causes of human cancers and diseases, which include exposure to environmental chemicals and other toxicants. This text considers the dietary habits and nutritional factors that play an important role in the causation and development of several human cancers, including cancer of the breast, colon, prostate, and other organs. Other chapters discuss the toxic effects of several xenobiotics that involve free-radical mechanisms. Biochemists, biophysicists, microbiologists, organic chemists, food chemists, and medical scientists will find this book extremely useful.

Table of Contents:
Sponsors Foreword Preface VI. Oxidation Mechanisms in Carcinogenesis Oxidations Catalyzed by Prostaglandin H Synthase Oxidation Reactions by Endoperoxide Synthase Molecular Mechanisms for the Peroxidase Catalyzed Activation of Arylamine Carcinogens to Cytotoxic Metabolites Inhibitors of Carcinogenesis The Role of Iron in Asbestos-Catalyzed Damage to Lipids and DNA Selective Enhancement of Free Radicals by cis-Unsaturated Fatty Acids in Tumor Cells as a Strategy to Kill Tumor Cells In Vitro and In Vivo Inhibition of Binding of Aflatoxin ?1 to Renal DNA by Dehydroepiandrosterone VII. Enzymes in Prostaglandin and Leukotriene Metabolism Prostaglandin H Synthase Peroxide Tone and Its Consequences Involvement of Glutathione Peroxidases in Prostaglandin Biosynthesis Non-Cyclooxygenase Prostaglandin Biosynthesis: Formation of PGA3 Isomers Via an Allene Oxide Non-Cyclooxygenase Oxidative Formation of a Series of Novel Prostaglandins: Ramifications for the Measurement of Eicosanoids in Biological Fluids Lipoxins: Bioactive Eicosanoids Generated by Lipoxygenase Interactions Novel Hepoxilin Glutathione Conjugates with Biological Activity Optically Pure Allylic Hydroperoxides: Mechanisms for Hydroperoxide Rearrangements Arachidonate 12-Lipoxygenases The Unique Characteristics of the Purified 5-Lipoxygenase from Potato Tubers and the Proposed Mechanism of Formation of Leukotrienes and Lipoxins Arachidonic Acid Oxidation and Platelet Function Role of Eicosanoids of the Lipoxygenäse Pathway in Vertebrate Reproduction Endogenous Formation of Leukotriene C4 In Vivo and Characterization of Novel Metabolites Formed In Vitro and In Vivo VIII. Lipid Peroxidation and Other Nonenzymatic Reactions of Oxygen Vitamin E In Vivo Interaction of Glutathione and a-Tocopherol in the Inhibition of Lipid Peroxidation in Rat Liver Microsomes Glutathione and Vitamin E and the Control of Lipid Peroxidation of Rat Liver Nuclei Mechanisms of Vitamin E Control of Lipid Peroxidation: Regeneration, Synergism, Asymmetry, Migration, and Metal Chelation Vanadium as a Biological Hydrogen-Abstractive Agent Constitutive and Inducible Repair Systems in Oxidative Stress Oxidative Damage to Proteins Mediated by Singlet Oxygen Molecular Mechanisms of Oxidative Cell Damage Oxidative Myocardial Injury and Cardiac-Derived Experimental Systems Mitochondrial Generation of Hydroxyl Radical During Reperfusion of Ischemic Myocardium Role of Lipid Peroxides in Aging Hepatocellular Regeneration as a Determinant of Halomethane Hepatotoxicity Structure Activity Correlations of 1,4-Dihydropyridines as Reducing Agents Modulation of Tubulin Tyrosinolation in Human Neutrophils by the NADPH Oxidase-Mediated Respiratory Burst Isolation and Characterization of a Mammalian Hydroxyacid-Oxoacid Transhydrogenase Author Index Key Word Index Symposium Delegates


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Product Details
  • ISBN-13: 9780125845526
  • Publisher: Elsevier Science Publishing Co Inc
  • Publisher Imprint: Academic Press Inc
  • Language: English
  • Weight: 920 gr
  • ISBN-10: 0125845529
  • Publisher Date: 15 Jan 1991
  • Binding: Hardback
  • No of Pages: 588


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