Analytical Chemistry of Polycyclic Aromatic Compounds

Analytical Chemistry of Polycyclic Aromatic Compounds focuses on the chemical and physical properties of the polycyclic aromatic compounds, critically evaluating various chromatographic and spectroscopic methods. This book discusses how gas chromatography and high-performance liquid chromatography can be both competitive and complementary analytical methods. Ancillary techniques of both are emphasized for the structural elucidation of individual polycyclic aromatic compounds in complex mixtures. The merits of spectroscopic methods in both structural work and quantitation are also described. This text likewise provides background information concerning the chemistry, occurrence, and toxicology of polycyclic aromatic compounds, including the isolation of polycyclic aromatic compounds from a wide variety of materials and matrices. This publication is recommended to scientists involved with the study of polycyclic aromatic compounds, analysts who need to acquire routine data, and individuals charged with formulating environmental policies and drafting regulations.

Table of Contents:
Preface1 Physical and Chemical Properties I. Nomenclature II. Physical Properties III. Chemical Properties References2 Occurrence I. Formation II. Sources III. Distribution References3 Toxicology and Metabolism I. Introduction II. Toxicity III. Biological Testing IV. Structure-Activity Relationships V. Binding of PAC to Cellular and Subcellular Units VI. Metabolism VII. Analytical Methods References4 Collection, Extraction, and Fractionation I. Introduction II. Collection and Extraction III. Concentration and Clean-Up IV. Selected Analytical Schemes V. Isolation of the Nitrogen Heterocycle Fraction VI. Isolation of the Sulfur Heterocycle Fraction References5 Column, Paper, and Thin-Layer Chromatography I. Introduction II. Column Adsorption Chromatography III. Paper and Thin-Layer Chromatography IV. Gel Permeation Chromatography References6 High-Performance Liquid Chromatography I. Introduction II. Chromatographic Columns III. Gradient Elution Techniques IV. Detection Systems V. Capillary and Microbore Columns References7 Gas Chromatography I. Introduction II. Stationary Phases III. Capillary Gas Chromatography IV. Detectors and Ancillary Techniques V. Supercritical-Fluid Chromatography References8 Mass Spectrometry I. Introduction II. Electron Impact III. Chemical Ionization and Negative Ions IV. Metastable Ions and Collision Spectroscopy V. Field Ionization and Field Desorption VI. Photoionization References9 Ultraviolet Absorption and Luminescence Spectroscopy I. Introduction II. Ultraviolet Absorption III. Fluorescence IV. Phosphorescence V. Selective Quenching in Luminescence Analysis VI. Low-Temperature Luminescence VII. New Luminescence Methods References10 Nuclear Magnetic Resonance and Infrared Spectroscopy I. Introduction II. Continuous-Wave 1H NMR III. Pulse Fourier-Transform NMR IV. Fourier-Transform IR References11 Approaches to Problem Solving in PAC Analysis I. Introduction II. Priority Pollutants in Contaminated Water III. Analysis of Methylchrysenes ReferencesAppendix 1: Polycyclic Aromatic Hydrocarbons: Names, Formulas, Structures, and NumberingAppendix 2: Polycyclic Aromatic Heterocycles Containing One Nitrogen Atom: Names, Formulas, Structures, and NumberingAppendix 3: Polycyclic Aromatic Heterocycles Containing One Sulfur Atom: Names, Formulas, Structures, and NumberingAppendix 4: Polycyclic Aromatic Heterocycles Containing One Oxygen Atom: Names, Formulas, Structures, and NumberingAppendix 5: Polycyclic Aromatic Compounds That Have Been Tested for Carcinogenic ActivityIndex