Case Files Biochemistry: (LANGE Case Files)

Review/USMLE/Biochemistry. This book presents real-life clinical cases for the basic sciences and USMLE Step 1. Clinical correlations are increasingly emphasized in the teaching of basic medical science. Students, therefore, need exposure to clinical cases to pass course exams and ace the USMLE Step 1. This book presents 46 real-life clinical cases illustrating essential concepts in biochemistry. Each case includes an easy-to-understand discussion correlated to key basic science concepts, definitions of key terms, biochemistry pearls, and USMLE-style review questions. This interactive learning system helps you to learn instead of memorize. It contains 46 clinical cases correlated to high-yield biochemistry concepts; biochemistry pearls highlight key points; USMLE-style comprehension questions with each case; and, primer on how to approach the basic sciences. Proven learning system improves exam scores.'"Case Files: Biochemistry" provides students with a compilation of scenarios very similar to those seen on the USMLE Step 1 and standardized tests. The explanations include everything you need to know and more about a particular disease. It is a well-rounded method of reviewing for the boards' - Sunitha J.Moonthungal, 3rd year medical student, St. George's University. '"Case Files: Biochemistry is a great way to integrate the application of basic science knowledge to clinical cases' - Arlene Chung, 4th year medical student, East Carolina University School of Medicine. McGraw-Hill Professional LANGE publishing for medical students since 1938.

Table of Contents:
Section 1: Approach to Basic Sciences and Biochemistry Section 2: 45 Cases Case 1 Gene Expression and Protein Synthesis Case 2 Methotrexate use (S phase chemotherapy) Case 3 HIV retrovirus polymerase agent Case 4 PCR test Case 5 Steroid messenger regulation of protein synthesis Case 6 Gel electrophoresis analysis for cystic fibrosis Case 7 Ribovirin use for influenza virus Case 8 Erythromycin mechanism (antibiotic) Case 9 Quinolone use (pelvic inflammatory disease) Case 10 Oncogenes and cancer Case 11 Oligonucleotide probe Case 12 Fragile X syndrome Case 13 Metabolism, ATP; Thiamine deficiency Case 14 Anaerobic metabolism (septic shock) Case 15 Cyanide poisoning Case 16 Rotenone (fish poison) toxicity Case 17 Folate deficiency Case 18 Carbon monoxide poisoning Case 19 Vitamin C deficiency Case 20 Malignant hyperthermia Case 21 Carbohydrate metabolism; False Pancreatitis (amylase) Case 22 Acute fatty liver of pregnancy (hypoglycemia) Case 23 Rhabdomyolysis (lactate) Case 24 Glucose intolerance Case 25 Hemolytic anemia (pyruvate kinase deficiency) Case 26 Fluctose intolerance Case 27 Increase dietary fiber Case 28 Somogi effect (nighttime hypoglycemia; morning hyperglycemia) Case 29 Muscle cramps Case 30 Tay Sach’s Case 31 Lipid metabolism; Hypercholesterolinemia Case 32 Gall stones Case 33 Bleeding after aspirin Case 34 Respiratory distress in newborn Case 35 Hypertriglyceridemia Case 36 Cholestasis of pregnancy Case 37 Statin agents and lowering of cholesterol Case 38 Protein metabolism (Starvation; conversion of amino acids into glucose) Case 39 Cirrhosis with ammonia accumulation Case 40 Cystinuria (congenital defect in transport of cysteine) Case 41 Anorexia nervosa Case 42 Tylenol overdose Case 43 Vegetarian Case 44 Gout Case 45 Biochemical Endocrinology; Iodine deficiency (hypothyroidism) Case 46 Diabetes insipidus Case 47 Acromegaly Case 48 Menopause Case 49 Addison’s disease Case 50 Parathyroid hormone

About the Author :
Eugene C. Toy, MD is a dual certified family physician and ob/gyn. He is the John S. Dunn Senior Academic Chair and Program Director of the Obstetrics and Gynecology Residency Program; Vice Chair of Academic Affairs in the Department of Obstetrics and Gynecology at The Methodist Hospital--Houston; Clerkship Director and Assistant Clinical Professor in the Department of Obstetrics and Gynecology at The University of Texas--Houston Medical School (Houston, Texas). William E. Seifert, Jr., PhD is Senior Lecturer and Medical Biochemistry Course Director in the Department of Biochemistry and Molecular Biology at The University of Texas—Houston Medical School. Henry W. Strobel, PhD is Professor in the Department of Biochemistry and Molecular Biology; Assistant Dean for Student Affairs; and Associate Dean for Faculty Affairs at The University of Texas—Houston Medical School. Konrad P. Harms, MD is Associate Program Director and Director of Academic Development for the Obstetrics and Gynecology Residency Program at The Methodist Hospital in Houston, Texas.