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Stratégie d'identification de composés anticancéreux à base de plantes

Stratégie d'identification de composés anticancéreux à base de plantes


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About the Book

Stratégie d'identification de composés anticancéreux d'origine végétale validée principalement par l'étude de l'efficacité de quatre médicaments anticancéreux, à savoir la vinblastine, le méthotrexate, l'étoposide et le cisplatine, sur des semis de pois chiche (Lathyrus sativus L.) en germination, en tenant compte d'attributs tels que l'indice mitotique et la longueur des semis. Les semis sont également traités avec de la colchicine, puis avec les médicaments. La colchicine induit la formation de cellules polyploïdes, qui est une caractéristique des cellules cancéreuses. En outre, les potentialités inhibitrices des substances testées sont également étudiées en relation avec la croissance des callosités. La formation de callosités ressemble à la croissance tumorale et son inhibition représente le potentiel des médicaments. Des études biochimiques et moléculaires révèlent que les modes d'action des médicaments anticancéreux sont presque similaires dans le système végétal et humain. De plus, le domaine de liaison des médicaments a également été étudié en comparaison avec des espèces végétales et des êtres humains. L'objectif de ce travail est d'évaluer le potentiel efficace de certains médicaments anticancéreux connus afin de déterminer si les plantes peuvent être utilisées comme modèle pour le criblage préliminaire de plusieurs composés prometteurs. Le système végétal est rentable et pratique à utiliser.


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Product Details
  • ISBN-13: 9786208921330
  • Publisher: Editions Notre Savoir
  • Publisher Imprint: Editions Notre Savoir
  • Height: 229 mm
  • No of Pages: 108
  • Returnable: N
  • Weight: 209 gr
  • ISBN-10: 6208921333
  • Publisher Date: 17 Jun 2025
  • Binding: Paperback
  • Language: French
  • Returnable: N
  • Spine Width: 7 mm
  • Width: 152 mm


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