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Protótipo de ensaio imunodiagnóstico baseado em antígenos novos para fasciolose

Protótipo de ensaio imunodiagnóstico baseado em antígenos novos para fasciolose


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About the Book

A fasciolose é uma doença zoonótica causada por F. hepatica e F. gigantica. A doença é considerada um problema grave para a saúde humana. É também uma ameaça que prejudica a produtividade animal em todo o mundo, causando grandes perdas económicas. Embora a terapia leve à cura total, a necessidade de um diagnóstico rápido é fundamental para o tratamento precoce e para evitar perdas. O diagnóstico fecal convencional baseado na deteção de ovos de Fasciola provou ser pouco fiável devido à natureza do parasita. Para resolver esse problema, é necessária uma ferramenta imunodiagnóstica rápida e precisa. Muitos métodos baseados em anticorpos permitem a deteção precoce, mas nenhum deles consegue distinguir entre infecções atuais e antigas e não podem ser utilizados no acompanhamento. Este livro descreve as etapas do estabelecimento e avaliação primária de uma ferramenta promissora e nova baseada em antígenos no formato sELISA. Baseia-se num imunógeno de 40 kDa de origem E/S, isolado de ovelhas infectadas artificialmente. O teste é altamente específico na deteção da infecção por F. gigantica em ovelhas. No entanto, são necessários mais testes para avaliar todo o seu potencial e para um maior desenvolvimento para também ser utilizado em seres humanos.


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Product Details
  • ISBN-13: 9786208919306
  • Publisher: Edicoes Nosso Conhecimento
  • Publisher Imprint: Edicoes Nosso Conhecimento
  • Height: 229 mm
  • No of Pages: 92
  • Returnable: N
  • Weight: 186 gr
  • ISBN-10: 6208919304
  • Publisher Date: 31 May 2025
  • Binding: Paperback
  • Language: Portuguese
  • Returnable: N
  • Spine Width: 6 mm
  • Width: 152 mm


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