About the Book
This special topic issue of 'Neurodegenerative Diseases' contains contributions discussing the subject in-depth. 'Neurodegenerative Diseases' is a well-respected, international peer-reviewed journal in Neurobiology. Special topic issues are included in the subscription.
Table of Contents:
Preface: Adlkofer, F.X.; Thurau, K.; Tyrosine 687 Phosphorylated Alzheimer's Amyloid Precursor Protein Is Retained Intracellularly and Exhibits a Decreased Turnover Rate: Rebelo, S.; Vieira, S.I.; Esselmann, H.; Wiltfang, J.; da Cruz e Silva, E.F.; da Cruz e Silva, O.A.B.; Curcumin Derivatives Inhibit or Modulate Beta-Amyloid Precursor Protein Metabolism: Narlawar, R.; Baumann, K.; Schubenel, R.; Schmidt, B.; Receptor- and Non-Receptor Tyrosine Kinases Induce Processing of the Amyloid Precursor Protein: Role of the Low-Density Lipoprotein Receptor-Related Protein: Minopoli, G.; Passaro, F.; Aloia, L.; Carlomagno, F.; Melillo, R.M.; Santoro, M.; Forzati, F.; Zambrano, N.; Russo, T.; Amyloid Precursor Protein and Presenilin Involvement in Cell Signaling: Venezia, V.; Nizzari, M.; Carlo, P.; Corsaro, A.; Florio, T.; Russo, C.; Signal Peptide Peptidases and Gamma-Secretase: Cousins of the Same Protease Family? Fluhrer, R.; Haass, C.; BACE1 Expression and Activity: Relevance in Alzheimer's Disease: Zacchetti, D.; Chieregatti, E.; Bettegazzi, B.; Mihailovich, M.; Sousa, V.L.; Grohovaz, F.; Meldolesi, J.; BACE1 and Mutated Presenilin-1 Differently Modulate A[beta]40 and A[beta]42 Levels and Cerebral Amyloidosis in APPDutch Transgenic Mice: Herzig, M.C.; Paganetti, P.; Staufenbiel, M.; Jucker, M.; Development of a Novel Yeast Cell-Based System for Studying the Aggregation of Alzheimer's Disease-Associated A[beta] Peptides in vivo: von der Haar, T.; Josse, L.; Wright, P.; Zenthon, J.; Tuite, M.F.; Novel Processing of Notch 1 within Its Intracellular Domain by a Cysteine Protease: Fassa, A.; Parisiadou, L.; Robakis, N.K.; Efthimiopoulos, S.; Study on the Putative Contribution of Caspases and the Proteasome to the Degradation of Aph-1a and Pen-2: Dunys, J.; Kawarai, T.; Giaime, E.; Wilk, S.; Herrant, M.; Auberger, P.; St. George-Hyslop, P.; Alves da Costa, C.; Checler, F.; Increased A[beta] Production Leads to Intracellular Accumulation of A[beta] in Flotillin-1-Positive Endosomes: Rajendran, L.; Knobloch, M.; Geiger, K.D.; Dienel, S.; Nitsch, R.; Simons, K.; Konietzko, U.; Peripheral Site Acetylcholinesterase Blockade Induces RACK1-Associated Neuronal Remodeling: Farchi, N.; Ofek, K.; Podoly, E.; Dong, H.; Xiang, Y.-Y.; Diamant, S.; Livnah, O.; Li, J.; Hochner, B.; Lu, W.-Y.; Soreq, H.; A Systematic Review and Meta-Analysis of CSF Neurofilament Protein Levels as Biomarkers in Dementia: Petzold, A.; Keir, G.; Warren, J.; Fox, N.; Rossor, M.N.; Frequency of the LRRK2 G2019S Mutation in Siblings with Parkinson's Disease: Lesage, S.; Leclere, L.; Lohmann, E.; Borg, M.; Ruberg, M.; Durr, A.; Brice, A.; and the French Parkinson's Disease Genetic Study Group; Caenorhabditis elegans as a Model System for Parkinson's Disease: Schmidt, E.; Seifert, M.; Baumeister, R.; Glia Protects Neurons against Extracellular Human Neuromelanin: Depboylu, C.; Matusch, A.; Tribl, F.; Zoriy, M.; Michel, P.P.; Riederer, P.; Gerlach, M.; Becker, S.; Oertel, W.H.; Hoglinger, G.U.; Frontotemporal Lobar Degeneration with Ubiquitin-Positive Inclusions: A Molecular Genetic Update: van der Zee, J.; Gijselinck, I.; Pirici, D.; Kumar-Singh, S.; Cruts, M.; Van Broeckhoven, C.; Frontotemporal Dementia with Tau Pathology: Gasparini, L.; Terni, B.; Spillantini, M.G.; Small Molecule Inducers of Heat-Shock Response Reduce polyQ-Mediated Huntingtin Aggregation. A Possible Therapeutic Strategy: Herbst, M.; Wanker, E.E.; Differential Modulation of Neurite Growth by the S- and the L-Forms of bag1, a Co-Chaperone of Hsp70: Frebel, K.; Wiese, S; Funk, N.; Puhringer, D.; Sendtner, M.; Pathway Proteomics and Chemical Proteomics Team Up in Drug Discovery: Hopf, C.; Bantscheff, M.; Drewes, G.
