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Foldamers: Structure, Properties and Applications

Foldamers: Structure, Properties and Applications


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About the Book

This truly comprehensive treatise of foldamers, from synthesis to applications in bio-, material-, and nanoscience is at once an introduction to the topic, while providing in-depth accounts on various aspects clearly aimed at the specialist.
The book is clearly structured, with the first part concentrating on structure and foldamer design concepts, while the second part covers functional aspects from properties to applications. The international team of expert authors provides overviews of synthetic approaches as well as analytical techniques.

Table of Contents:
Foreword
STRUCTURE: FOLDAMER DESIGN CONCEPTS
Foldamers Based on Local Conformation Preferences
Foldamers Based on Remote Intrastrand Interactions
Foldamers Based on Solvophobic Effects
Foldamer Hybrids: Defined Supramolecular Structures from Flexible Molecules
Control of Polypeptide Chain Folding and Assembly
Simulation of Folding Equilibria
FUNCTION: FROM PROPERTIES TO APPLICATIONS
Foldamer-based Molecular Recognition
Biological Application of Foldamers
Protein Design
Nucleic Acid Foldamers: Design, Engineering and Selection of Programmable Biomaterials with Recognition, Catalytic and Self-assembly Properties
Helically Folding Polymers
Polyisocyanides: Stiffened Foldamers
Foldamers at Interfaces




About the Author :
Stefan Hecht obtained his doctorate under the guidance of Prof. Jean M. J. Frechet at the University of California. After becoming a research investigator at Berlin, he is now group leader at the Max-Planck-Institut fur Kohlenforschung. He has been a fellow of the Studienstiftung des Deutschen Volkes and has received both the Sofja Kovalevskaja Award of the Alexander von Humboldt Foundation as well as the MIT Technology Review Top 100 Young Innovator Award.

Ivan Huc received his PhD in 1994 from the Universite of Paris VI, jointly supervided by Dr. C. Rolando (Ecole Normale Superieure) and Prof. J. Rebek Jr. (MIT). After a post-doctoral period with Dr. J.-P. Behr in Illkirch, he received a CNRS researcher position in Nobel Prize winner Prof. J.-M. Lehn's laboratories in Strasbourg, where he stayed until 1998. Since then, he has been a group leader at the Institut Europeen de Chimie et Biologie (Bordeaux) where he holds a research director position.


Review :

“Hecht and Huc have made an important contribution to the literature of foldamers. The greatest strength of their volume is that it presents the diversity and open-ended possibilities offoldamer-based research, rather than trying to rigidly categorize the field. Chemists from all subdisciplines will find it an inspiring invitation to join in solving the challenges and exploiting the potential of this fascinating arena of molecular science.”  (JACS, 2008)

"Anyone who considers joining this field, or who just wants to know what is being done in the area, will be fortunate to have the efforts of editors Hecht and Huc at hand." (Angewandte Chemie International Edition, January 2008)

"…Foldamers is a delightful treatise on the subject area, provided that the reader is bent towards the biological realm. … Such versatility is hard to find, and the authors and editors should be commended for their hard work." (ChemMedChem, December 2007)

 

"...sollte somit sowohl äußerst wertvolle Anregungen für Forschende als auch wichtige Aspekte für Forschende als auch wichtige Aspekte für moderne Vorlesungen über Polymersynthese liefern."
Nachrichten aus der Chemie
1/2008

"Jeder, der auf diesem Gebiet forschen oder sich einen Überblick über den aktuellen Forschungsstand verschaffen will, wird sich glücklich schätzen, das Buch zur Hand zu haben."
Angewandte Chemie
2008-120/4


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Product Details
  • ISBN-13: 9783527315635
  • Publisher: Wiley-VCH Verlag GmbH
  • Publisher Imprint: Blackwell Verlag GmbH
  • Height: 249 mm
  • No of Pages: 456
  • Spine Width: 20 mm
  • Weight: 771 gr
  • ISBN-10: 3527315632
  • Publisher Date: 11 May 2007
  • Binding: Hardback
  • Language: English
  • Returnable: N
  • Sub Title: Structure, Properties and Applications
  • Width: 175 mm


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