Progressive Supranuclear Palsy: Diagnosis, Pathology, and Therapy
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Home > Medicine & Health Science textbooks > Medical specialties, branches of medicine > Neurology and clinical neurophysiology > Progressive Supranuclear Palsy: Diagnosis, Pathology, and Therapy: (42 Journal of Neural Transmission. Supplementa)
Progressive Supranuclear Palsy: Diagnosis, Pathology, and Therapy: (42 Journal of Neural Transmission. Supplementa)

Progressive Supranuclear Palsy: Diagnosis, Pathology, and Therapy: (42 Journal of Neural Transmission. Supplementa)


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About the Book

This monograph summarizes recent developments in clinical and basic research in progressive supranuclear palsy (PSP). This disorder is the second most common cause of parkinsonism seen in practice. Only recently we have been able to diagnose it regularly in living patients. There is an outporing of new interest in PSP in many research centers around the world and this volume is an expression of this research interest. Different clinical and basic subjects on PSP are covered in this monograph by individual experts in the field, incorporating their latest advances in research. With this book the reader will be able to have on hand the most recent advances on PSP covering areas such as epidemiology, neuropathology and neurophysiological, and neuroimaging aspects, as well as recent advances in neurochemistry, neuropathology and treatment of this disorder.

Table of Contents:
Clinical aspects.- Historical notes.- Clinical diagnosis and diagnostic criteria of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome).- Eyelid motor abnormalities in progressive supranuclear palsy.- he auditory startle response in progressive supranuclear palsy.- Differential diagnosis of PSP.- Cognitive disturbances in progressive supranuclear palsy.- Progressive supranuclear palsy and corticobasal ganglionic degeneration: differentiation by clinical features and neuroimaging techniques.- Neuroimage analysis, cerebral blood flow, and metabolism.- Magnetic resonance imaging in progressive supranuclear palsy and other parkinsonian disorders.- Clinical progressive supranuclear palsy: differential diagnosis by IBZM-SPECT and MRI.- PET studies in progressive supranuclear palsy.- Morphological aspects.- The neuropathology of progressive supranuclear palsy.- Neurofibrillary pathology in progressive supranuclear palsy (PSP).- Antigenic determinant properties of neurofibrillary tangles. Relevance to progressive supranuclear palsy.- Cortical tangles in progressive supranuclear palsy.- Vascular progressive supranuclear palsy.- Biochemical aspects.- Cholinergic and peptidergic systems in PSP.- Brain monoamines in progressive supranuclear palsy—comparison with idiopathic Parkinson’s disease.- Alterations of neurotransmitter receptors and neurotransmitter transporters in progressive supranuclear palsy.- Changes in aminergic receptors in a PSP postmortem brain: correlation with pathological findings.- Epidemiology and treatment.- The epidemiology of PSP.- Cholinergic approaches to the treatment of progressive supranuclear palsy.- Therapy for progressive supranuclear palsy: past and future.


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Product Details
  • ISBN-13: 9783211825419
  • Publisher: Springer Verlag GmbH
  • Publisher Imprint: Springer Verlag GmbH
  • Height: 235 mm
  • No of Pages: 293
  • Returnable: Y
  • Width: 155 mm
  • ISBN-10: 321182541X
  • Publisher Date: 14 Jul 1994
  • Binding: Paperback
  • Language: English
  • Returnable: Y
  • Series Title: 42 Journal of Neural Transmission. Supplementa


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