Immunology: Essential and Fundamental

Table of Contents:
Introduction to Immunology; Innate Immunity or Non-Adaptive Immunity; Introduction; The Main Players; The Innate Immune Response; Complement; Introduction; The Classical Pathway; The Lectin Pathway of Complement Activation; The Alternative Pathway of Complement Activation; Terminal Pathway; Role of Complement in Health and Disease; Regulation of the Complement Cascade; Complement Receptors; Entities of the Adaptive Immune Response: Immunogens; Introduction; Immunogens and Antigens; Types of Antigens; Factors Influencing Immunogenicity; Entities of the Adaptive Immune Response: Lymphoid System; Introduction; Primary Lymphoid Organs; Secondary Lymphoid Organs; The Accessory Cells; Molecules of Adaptive Immune Recognition: Antigen Recognition Receptors; Introduction; BcR; TcR; Effect of Costimulators on B and T Cell Signal Transduction Pathways; Molecules of Immune Recognition: Antigen Presenting Molecules; Introduction; MHC Class I Molecules; MHC Class II Molecules; Organisation of MHC Genes; Polygenism and Polymorphism in the MHC Molecules; CDI; The Lymphocytes; Introduction; The B Lymphocytes; The T Lymphocytes; Humoral Immunity; Introduction; Primary Humoral Response; Secondary Humoral Response; Ig Synthesis; Ig Structure; Classes of Antibodies; Role of Ig in Immunity; Ig Receptors; Genetic Mechanisms of Immune Diversity; Introduction; V(D)J Recombination; Regulation of V(D)J Recombination; Somatic Hypermutation and Class Switch Recombination (CSR); Cell-Mediated Immunity; Introduction; Mechanisms of Cell-Mediated Cytotoxicity; Immune Tolerance; Introduction; Central Tolerance; Peripheral Tolerance; Tolerance Induction; Transplantation Immunology; Introduction; Antigens Involved in Graft Rejection; Allorecognition; Graft Rejection; GVHD; Immunosuppressive Therapies; Blood Transfusion; Autoimmunity; Introduction; Interplaying Factors; Triggering Factors; Mechanisms of Damage; Diagnosis and Treatment; Hypersensitivity; Introduction; Hypersensitivity type I; Hypersensitivity type II; Hypersensitivity type III; Hypersensitivity type IV; Cancer and the Immune System; Introduction; Effectors of Anti-tumour Immunity; Tumour Immune Evasion; Treatment; AIDS; Introduction; The Virus; HIV and the Immune System; Treatment

Review :
"This book views Immunology in the context of everyday human life. It challenges scientific imagination by bringing the interested reader sidetracks, digressions as they may seem, that add a different dimension to the subject being discussed. Immunology: Essential and Fundamental constantly reminds the reader that the subject that it gets its name from, although being an extensively specialized field, must be viewed in the context of the human body, the individual, and the society s/he inhabits. It helps us appreciate that Immunology goes beyond being a compartmentalized and specialized field and enriches our understanding of the big picture." - Prof. Rob Benner Head, Department of Immunology, Erasmus MC University Medical Center, Rotterdam, The Netherlands"