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The Immunoassay Handbook

The Immunoassay Handbook


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About the Book

Immunoassays are now an essential part of clinical chemistry and research in the life sciences. They have helped to improve analytical work because of their ability to measure minute concentrations, in complex biological fluids, in a relatively short length of time. We depend on them to provide consistent results. However, the biological nature of the reagents, and the diversity of the samples being assayed, are just two of the root causes of problems which affect every immunoassay laboratory from time to time. Also the equipment used can cause problems if not properly designed and maintained. This book contains a separate section for each of the main types of fault that can occur, explaining what information is needed to solve the fault, how to investigate it and what could have caused it. Also included are sections on quality control and the principles of troubleshooting as well as a guide to diagnosing curve-fitting programme problems painlessly and a section on diagnosing problems in automated systems. "The Immunoassay Handbook" is designed to help solve problems with competitive and immunometric assays, and with enzyme, radioactive, fluorescent, luminescent and other signal sources. It has been especially designed for in-house and commercial assays from a variety of manufacturers.

Table of Contents:
Contributors - Expert Advisors - Preface - Acknowledgements - PART 1 PRINCIPLES - Principles - Components - Concepts - Calibration Curve-fitting - Immunological Biosensors - PART 2 PRODUCTS - Introduction - Abbott IMx - Baxter Stratus Immunoassay Systems - Boehringer Mannheim ES 300 Immunoassay System - Ciba Corning ACS: 180 - DPC Milenia - DPC Immulite - Hybritech ICON & Tandem ICON QSR - Kodak Amerlex-M Radioimmunoassays - Kodak Amerlite Modular System - Kodak Amerlite Processing Center - Kodak SureCell - Microgenics CEDIA - PB Diagnostics OPUS, OPUS PLUS and OPUS MAGNUM - Serono MAIAclone - Serono MAIA - Serono Serozyme - Serono SR1 Automated Immunoassay System - Syva ETS Plus System - Syva MicroTrak - Syva MicroTrak EIA - Syva Vista Immunoassay System - TOSOH AIA - 600 & AIA - 1200 - Unipath Clearblue One Step, Clearplan One Step and Clearview - Wallac DELFIA - PART 3 LABORATORY MANAGEMENT - Subject Preparation, Sample Collection and Handling - Method Evaluation - Laboratory Quality Assurance - Clinical Laboratory Improvement Amendments of 1988 - Immunoassay Troubleshooting Guide - PART 4 APPLICATIONS - Thyroid - The Adrenal Cortex - Calcium Metabolism - Infertility - Hirsutism and Virilization in the Female - Pregnancy - Growth - Diabetes Mellitus - Hematology - Heart - Cancer Markers - Allergy - Autoimmune Disease - Sexually Transmitted Diseases - Congenital Diseases of Microbiological Origin - Hepatitis - Miscellaneous Diseases of Microbiological Origin - Therapeutic Drug Monitoring - Drugs of Abuse - Miscellaneous - Immunoassay Applications in Life-Science Research - Immunoassay Applications in Veterinary Diagnostics - Company Addresses - Index


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Product Details
  • ISBN-13: 9780333511794
  • Publisher: Nature Publishing Group
  • Publisher Imprint: Nature Publishing Group
  • Height: 252 mm
  • Width: 195 mm
  • ISBN-10: 0333511794
  • Publisher Date: 14 Jun 1994
  • Binding: Hardback
  • Weight: 1601 gr


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